| 摘要 |
Compounds of the formula (see formula I) wherein X is O or S; Y is O or S; R1 is hydrogen, halogen, C1-C4 alkyl or C1-C4 alkoxy; R2 is hydrogen, halogen, C1-C4 alkyl, C1-C4 alkoxy, C2-C4 alkenyl, C2-C4 alkenyloxy, C2-C4 alkynyl, C2-C4 alkynyloxy, mono-, di- or tri-halomethyl, trifluoromethoxy, C1-C4 alkylthio, C3-C4 branched alkylthio, nitro, or cyano; R3 is hydrogen, halogen, methyl, mono-, di- or tri- halomethyl; R4 is a) C3-C8 cycloalkyl substituted by one or more C1-C4 alkyl, preferably one or two methyl; or b) (see formula II) wherein R6 and R7 are independently, hydrogen or linear or branched, C1-C4 alkyl, C2-C4 alkenyl, or C2-C4 alkynyl, and R8 is C3-C8 cycloalkyl substituted by one or more C1-C4 alkyl; and R5 is an acyclic or cyclic side chain as defined herein. These compounds are useful for inhibiting the growth or replication of retroviruses such as HIV.
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