摘要 |
Gelatin-free capsule for use in oral administration of medicines cosmetic or bath applications, or dietary supplements can be prepared from compositions comprising: a) 8-50 % by weight of water- dispersible or water-soluble plasticizer, b) 0.5 to 12 % by weight .kappa.-carrageenan, c) 0 to 60 % dextrins, and d) 1 % to 95 % by weight water, with the .kappa.-carrageenan comprising at least 50 % by weight of all gums forming or contributing to formation of thermoreversible gels in th e composition. A capsule for oral administration or cosmetic application may comprise a fill material to be administered to a patient or subject and a capsule, the capsule comprising an aqueous based film compring: a) water-dispersible or water-soluble plasticizer, and b) carrageenan, with the carrageenan comprising at leat 50 % or 75 % by weight of .kappa.-carrageenan, and the carrageenan comprising at leat 5 0 % or 75 % by weight of all gums which form or contribute to the formation of thermoreversible gels. A process for forming the capsules m ay comprise heating the composition, casting or extruding the composition into a film, gelling the composition by cooling, associating a fill material with the gelled composition (usually as a film) and sealing the film about the fill material.
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