发明名称 NON-GELATIN SUBSTITUTES FOR ORAL DELIVERY CAPSULES, THEIR COMPOSITION AND PROCESS OF MANUFACTURE
摘要 Gelatin-free capsule for use in oral administration of medicines cosmetic or bath applications, or dietary supplements can be prepared from compositions comprising: a) 8-50 % by weight of water- dispersible or water-soluble plasticizer, b) 0.5 to 12 % by weight .kappa.-carrageenan, c) 0 to 60 % dextrins, and d) 1 % to 95 % by weight water, with the .kappa.-carrageenan comprising at least 50 % by weight of all gums forming or contributing to formation of thermoreversible gels in th e composition. A capsule for oral administration or cosmetic application may comprise a fill material to be administered to a patient or subject and a capsule, the capsule comprising an aqueous based film compring: a) water-dispersible or water-soluble plasticizer, and b) carrageenan, with the carrageenan comprising at leat 50 % or 75 % by weight of .kappa.-carrageenan, and the carrageenan comprising at leat 5 0 % or 75 % by weight of all gums which form or contribute to the formation of thermoreversible gels. A process for forming the capsules m ay comprise heating the composition, casting or extruding the composition into a film, gelling the composition by cooling, associating a fill material with the gelled composition (usually as a film) and sealing the film about the fill material.
申请公布号 CA2341024(C) 申请公布日期 2007.04.03
申请号 CA19992341024 申请日期 1999.08.24
申请人 BANNER PHARMACAPS, INC. 发明人 GENNADIOS, ARISTIPPOS
分类号 A61K9/48;A61K9/64;A61K47/36 主分类号 A61K9/48
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