摘要 |
<p>The invention discloses an improved process for preparing non-hygroscop ic Azithromycin dihydrate wherein Azithromycin monhydrate can be converted to Azithromycin dihydrate with continous stirring/agitation in presence of a mixture of at least one solvent such as herein described and water till non- hygroscopic crystals of Azithromycin dihydrate are obtained.The solvent in t he process of the invention can be selected from the group comprising dimethylformamide, dimethylacetamide, acetonitrile and iso-propanol,</p> |