Cloning and sequencing of pyruvate decarboxylase (PDC) genes from bacteria and uses therefor

摘要

Disclosed are isolated nucleic acids molecules which encode polypeptides capable of decarboxylating pyruvate into acetaldehyde. Also disclosed are recombinant expression vectors containing such nucleic acid molecules, recombinant host cells comprising the expression vectors, host cells further comprising other ethanologenix enzymes, and methods for producing useful substances, e.g., acetaldehyde and ethanol, using such host cells.