发明名称 SUBSTITUTED PYRIMIDINON AND PYRIDON COMPOUNDS AND METHODS OF APPLICATION
摘要 The new substituted pyrimidon and pyridon compounds are effective for the preventoion and treatment of diseases running with the mediation of TNF-alpha,IL-1beta, IL-6 and/or IL-6, and/or IL-8, as well as for easying of pains and in diabetes. The invention relates to new compounds, to their analogues, promedicamentous forms and their pharmaceutically acceptable salts, to pharmaceutical compositions and methods for the prevention and treatment of diseases and other sufferings or conditions occurring with inflammations, pains, diabetes, and others. The invention also relates to methods for the preparation of the compounds and to intermediate products for their preparation.
申请公布号 BG65129(B1) 申请公布日期 2007.03.30
申请号 BG19990103521 申请日期 1999.06.23
申请人 AMGEN INC. 发明人 SPOHR ULRIKE;MALONE MICHAEL;MANTLO NATHAN;ZABLOCKI JEFF
分类号 C07D239/42;A61K31/44;A61K31/443;A61K31/4436;A61K31/444;A61K31/445;A61K31/4545;A61K31/496;A61K31/506;A61K31/513;A61K31/519;A61K31/55;A61P1/04;A61P1/18;A61P3/10;A61P7/00;A61P9/02;A61P9/10;A61P11/06;A61P11/16;A61P17/00;A61P19/00;A61P19/02;A61P19/06;A61P19/08;A61P19/10;A61P21/00;A61P25/00;A61P25/28;A61P29/00;A61P35/00;A61P35/02;A61P37/06;C07D213/22;C07D213/64;C07D213/74;C07D213/75;C07D239/70;C07D401/04;C07D401/14;C07D405/00;C07D405/04;C07D405/06;C07D409/06;C07D409/14;C07D487/00;C07D487/04 主分类号 C07D239/42
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