| 发明名称 |
DNA19355 polypeptide, a tumor necrosis factor homolog |
| 摘要 |
A tumor necrosis factor homolog, identified as DNA19355, is provided. DNA19355 polypeptide has apoptotic activity in mammalian cancer cells and may be involved in proinflammatory responses. Nucleic acid molecules encoding DNA19355, chimeric molecules and antibodies to DNA19355 are also provided.
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| 申请公布号 |
US2007072263(A1) |
申请公布日期 |
2007.03.29 |
| 申请号 |
US20050123992 |
申请日期 |
2005.05.06 |
| 申请人 |
GENENTECH, INC. |
发明人 |
ASHKENAZI AVI J.;BAKER KEVIN P.;GODOWSKI PAUL J.;GURNEY AUSTIN L.;MARK MELANIE R.;MARSTERS SCOT A.;PITTI ROBERT M. |
| 分类号 |
A61K38/17;C12N15/09;A61K38/00;A61P35/00;C07H21/04;C07K14/525;C07K14/705;C07K16/24;C07K19/00;C12N1/18;C12N1/19;C12N1/21;C12N5/06;C12N5/10;C12N15/28;C12P21/02;C12P21/06;C12P21/08;C12R1/19 |
主分类号 |
A61K38/17 |
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