DIASTEREOMERIC PEPTIDES FOR MODULATING T CELL IMMUNITY
摘要
The present invention provides diastereomeric peptides derived from the T Cell Receptor alpha Transmembrane Domain, and lipophilic conjugates thereof, which peptides and conjugates are effective in preventing or treating T cell mediated inflammatory diseases. The invention provides pharmaceutical compositions comprising these diastereomeric peptides and conjugates, and uses thereof for therapy of inflammatory diseases, autoimmunity and graft rejection.
申请公布号
WO2007034490(A2)
申请公布日期
2007.03.29
申请号
WO2006IL01113
申请日期
2006.09.21
申请人
YEDA RESEARCH AND DEVELOPMENT CO. LTD., AT THE WEIZMANN INSTITUTE OF SCIENCE;SHAI, YECHIEL;COHEN, IRUN, R.;QUINTANA, FRANCISCO;GERBER, DORON