Matrices formed from a natural biodegradable material and that exhibit surface degradation in the presence of an enzyme are described. Matrices including a bioactive agent can be implanted or formed in a subject for release of the bioactive agent upon degradation of the matrix. The matrix can be provided in various forms, including coatings for implantable devices, implants, and in-situ formed matrices. The matrix can also be in the form of a medical device having a structure that is used to treat a medical condition.
申请公布号
WO2007035886(A1)
申请公布日期
2007.03.29
申请号
WO2006US36861
申请日期
2006.09.21
申请人
SURMODICS, INC.;CHUDZIK, STEPHEN, J.;BURKSTRAND, MICHAEL, J.;SWAN, DALE, G.;CHINN, JOSEPH, A.
发明人
CHUDZIK, STEPHEN, J.;BURKSTRAND, MICHAEL, J.;SWAN, DALE, G.;CHINN, JOSEPH, A.