发明名称 |
Novel nucleolar GTPases and method for controlling proliferation of cells |
摘要 |
There is provided an isolated polypeptide comprising an amino acid sequence at least 85% homologous to SEQ ID NO: 2 or SEQ ID N: 4, or a conservative variant thereof, wherein the polypeptide regulates proliferation of a cell. There is also provided an isolated polynucleotide encoding the polypeptide of the invention. There is also provided a method for inhibiting the proliferation of a cell, comprising altering the level of a polypeptide comprising an amino acid sequence at least 85% homologous to SEQ ID NO: 2 or SEQ ID NO: 4 in the cell, thereby inhibiting proliferation of the cell.
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申请公布号 |
US2007071755(A1) |
申请公布日期 |
2007.03.29 |
申请号 |
US20050235337 |
申请日期 |
2005.09.27 |
申请人 |
BALASUNDARAM DAVID;XIANMING DU;MAHALINGAM SUNDARASAMY |
发明人 |
BALASUNDARAM DAVID;XIANMING DU;MAHALINGAM SUNDARASAMY |
分类号 |
A61K39/395;C07H21/04;C12N9/16;C12P21/06;C12Q1/68;G01N33/574 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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