In Vivo Enhancement of Immune System Recognition of Neoplasms Following Treatment with an Oncolytic Virus or Gene Therapy Vector

摘要

This invention provides novel methods of treating or alleviating neoplasms and enhancing the efficacy of oncolytic viruses by administering an oncolytic virus to a mammal suffering from a neoplasm and subsequently administering an immunostimulant. The invention also provides methods of increasing immunorecognition of neoplastic cells.