ANTI-TUMOR METHODS USING MULTI DRUG RESISTANCE INDEPENDENT SYNTHETIC HSP90 INHIBITORS
摘要
<p>The present invention provides a method of treating an individual having an HSP90 mediated disorder comprising administering to said individual a pharmaceutical composition comprising a pharmaceutically effective amount of a synthetic heterocyclic HSP90 inhibitor, wherein the activity of the HSP90 inhibitor is substantially independent of multi drug resistance. In one embodiment, the activity of the HSP90 inhibitor is substantially independent of P-gp and MRP expression.</p>
申请公布号
WO2007035963(A2)
申请公布日期
2007.03.29
申请号
WO2006US37613
申请日期
2006.09.25
申请人
CONFORMA THERAPEUTICS CORPORATION;ZHANG, HONG;BURROWS, FRANCIS, J.