COMPOSITION AND METHOD FOR TREATING VIRAL INFECTION

摘要

Described is a novel polypeptide which has homology with human interferon alpha (14). The polypeptide, is characterised by the substitution of the amino acid residue at position (72) of the amino acid sequence so as to remove a residue which is capable of being glycosylated. The polypeptide of the invention may be produced by recombinant means in either a prokaryotic or eukaryotic production systems and is seem to mediate a potent anti-viral effect. Further provided is human interferon alpha (14) which is produced by recombinant means in systems other than a prokaryotic production system, said recombinantly derived alpha 14 being shown to have potent anti-viral activity.