USE OF P-SELECTIN GLYCOPROTEIN LIGAND 1 IN MODULATION OF HEMATOGENOUS METASTASIS OF LYMPHOMAS

摘要

The present invention relates to the use of P-selectin ligand 1 for the modulation of hematogenous metastasis of lymphomas. More specifically, it relates to the use of P-selectin glycoprotein ligan-1 and of molecules that impair the binding of P-selectin ligand in preventing metastasis, preferably metastasis in liver and spleen.