摘要 |
The invention concerns benzamide compounds of Formula (I), wherein R<SUP>1a</SUP>, R<SUP>1b</SUP>, R<SUP>1c</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, m and n have any of the meanings defined in the description; processes for their preparation, pharmaceutical compositions containing them and their use in the manufacture of a medicament for use as an antiproliferative agent in the prevention or treatment of tumours or other proliferative conditions which are sensitive to the inhibition of histone deacetylase (HDAC). |
申请人 |
ASTRAZENECA AB;ASTRAZENECA UK LIMITED;GIBSON, KEITH, HOPKINSON;STOKES, ELAINE, SOPHIE, ELIZABETH;WARING, MICHAEL, JAMES;ANDREWS, DAVID, MICHAEL;MATUSIAK, ZBIGNIEW, STANLEY;GRAHAM, MARK, ANDREW |
发明人 |
GIBSON, KEITH, HOPKINSON;STOKES, ELAINE, SOPHIE, ELIZABETH;WARING, MICHAEL, JAMES;ANDREWS, DAVID, MICHAEL;MATUSIAK, ZBIGNIEW, STANLEY;GRAHAM, MARK, ANDREW |