METHOD AND APPARATUS FOR DETECTION AND MONITORING OF T-WAVE ALTERNANS
摘要
A system and method are provided for assessing T-wave alternans (TWA) using cardiac EGM signals received from implanted electrodes. A T-wave signal parameter is measured from signals received by an automatic gain control sense amplifier. A TWA measurement is computed from a beat-by-beat comparison of T-wave parameter measurements or using frequency spectrum techniques. The TWA measurement magnitude and measurement conditions are used in detecting a clinically important TWA. TWA assessment further includes discriminating concordant and discordant TWA in a multi-vector TWA assessment, and determining the association of a TWA measurement with QRS alternans, mechanical alternans, and other physiological events. A prediction of a pathological cardiac event is made in response to a TWA assessment. A response to a cardiac event prediction is provided.
申请公布号
WO2007013911(A3)
申请公布日期
2007.03.29
申请号
WO2006US27995
申请日期
2006.07.19
申请人
MEDTRONIC, INC.;ZHOU, XIAOHONG;MULLEN, THOMAS, J.;GILLBERG, JEFFREY, M.;STADLER, ROBERT, W.
发明人
ZHOU, XIAOHONG;MULLEN, THOMAS, J.;GILLBERG, JEFFREY, M.;STADLER, ROBERT, W.