发明名称 |
A composition containing a complex comprising a metal ion and a carboxylate ligand having anti-inflammatory activity |
摘要 |
A pharmaceutical composition comprising a metal complex of a carboxylate having anti-inflammatory activity in a pharmaceutically acceptable carrier, wherein: (1) the composition has a colloidal structure, or forms a colloidal structure when administered to a human or animal, or is immiscible with water; (2) more than 80% of the total amount of the carboxylate having anti-inflammatory activity in the composition is present as part of a metal complex; and (3) less than 10% of the carboxylate having anti-inflammatory activity complexed with the metal dissociates from the metal over 12 months when the composition is stored in the absence of light at room temperature; but excluding compositions comprising a metal complex containing the ligand DMF. The invention also provides the use of the pharmaceutical composition in the treatment of inflammatory conditions in humans and animals. |
申请公布号 |
GB2430369(A) |
申请公布日期 |
2007.03.28 |
申请号 |
GB20060021511 |
申请日期 |
2005.03.30 |
申请人 |
MEDICAL THERAPIES LIMITED |
发明人 |
PETER LAY;TREVOR HAMBLEY;JANE WEDER;HUBERTUS L REGTOP;JOHN R BIFFEN;BRENDAN KENNEDY;NEAL DAVIES |
分类号 |
A61K31/19;A61K9/00;A61K31/192;A61K33/24;A61K33/30;A61K33/34;A61K45/06;A61P29/00;A61P29/02 |
主分类号 |
A61K31/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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