发明名称 4-(2-phenylsulfanyl-phenyl)-piperidine derivatives as serotonin reuptake inhibitors
摘要 The invention provides compounds represented by the general formula (I)wherein R, R, R, R, Rare independently selected from hydrogen, halogen, cyano, Calk (en/yn) yl, Calkyloxy, hydroxy-Calkyl, halo-Calkyl, halo-Calkyloxy or NRR, wherein Rand Rare independently selected from hydrogen, Calkyl; provided that at least one of R, R, R, R, R, R, R, Rand Ris different from hydrogen; and also provided that when Ris methyl, then at least one of R, R, R, R, R, R, Rand Ris different from hydrogen; or a salt thereof. The compounds are useful in the treatment of an affective disorder, including depression, anxiety disorders including general anxiety disorder and panic disorder and obsessive compulsive disorder.
申请公布号 ZA200507181(B) 申请公布日期 2007.03.28
申请号 ZA20050007181 申请日期 2004.04.02
申请人 H. LUNDBECK A/S. 发明人 BANG-ANDERSEN, BENNY;PUESCHL, ASK;JOERGENSEN, MORTEN RUHLAND, THOMAS;BRYAN STENSBOEL, TINE
分类号 A61K;A61K31/451;A61P;A61P25/00;C07D;C07D211/24;C07D407/12 主分类号 A61K
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