发明名称 Imino ether derivative compounds and drugs containing the compounds as the active ingredient
摘要 The compound represented by formula (I) <CHEM> (wherein R<1> and R<2> are cyclic group which may have a substituent(s) and so on.; W is a spacer of which main chain has an atom number of 1-6.; X is -O- and so on.; ringA is cyclic group which may have a substituent(s).; Y is a spacer of which main chain has an atom number of 1-6 and so on.; Z is acidic group.) a salt thereof, a solvent thereof or an N-oxide thereof or a prodrug thereof Since the compounds in the present invention have a regulatory activity for peroxisome proliferator activated receptor, the compounds in the present invention are useful as a preventive and/or therapeutic agent for diseases associating metabolic disorders (e.g., hypercholesterolemia, hyperlipoproteinemia, etc.), hyperlipidemia, atherosclerosis, hypertension, circulatory diseases, overeating, ischemic heart diseases, etc., an HDL cholesterol-elevating agent, an LDL cholesterol and/or a VLDL cholesterol-lowering agent and a drug for relief from risk factors of diabetes or metabolic syndrom.
申请公布号 ZA200508179(B) 申请公布日期 2007.03.28
申请号 ZA20050008179 申请日期 2005.10.10
申请人 ONO PHARMACEUTICAL CO., LTD. 发明人 ISHIDA, AKIHARU;NAKAYAMA, YOSHISUKE;KIDO, TOMOYUKI;KUSUDA, SHINYA;TAJIMA, HISAO;KITAMINE, TETSUYA
分类号 A61K;A61P;A61P3/04;A61P3/06;C07C;C07C251/54;C07D;C07D207/20;C07D209/08;C07D211/70;C07D213/30;C07D213/50;C07D213/53;C07D213/55;C07D231/12;C07D233/54;C07D249/08;C07D257/04;C07D277/04;C07D295/13;C07D307/52;C07D319/08;C07D333/22;C07D403/12;C07D407/10;C07D407/12;C07D409/04;C07D417/10 主分类号 A61K
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