发明名称 |
Imino ether derivative compounds and drugs containing the compounds as the active ingredient |
摘要 |
The compound represented by formula (I) <CHEM> (wherein R<1> and R<2> are cyclic group which may have a substituent(s) and so on.; W is a spacer of which main chain has an atom number of 1-6.; X is -O- and so on.; ringA is cyclic group which may have a substituent(s).; Y is a spacer of which main chain has an atom number of 1-6 and so on.; Z is acidic group.) a salt thereof, a solvent thereof or an N-oxide thereof or a prodrug thereof Since the compounds in the present invention have a regulatory activity for peroxisome proliferator activated receptor, the compounds in the present invention are useful as a preventive and/or therapeutic agent for diseases associating metabolic disorders (e.g., hypercholesterolemia, hyperlipoproteinemia, etc.), hyperlipidemia, atherosclerosis, hypertension, circulatory diseases, overeating, ischemic heart diseases, etc., an HDL cholesterol-elevating agent, an LDL cholesterol and/or a VLDL cholesterol-lowering agent and a drug for relief from risk factors of diabetes or metabolic syndrom. |
申请公布号 |
ZA200508179(B) |
申请公布日期 |
2007.03.28 |
申请号 |
ZA20050008179 |
申请日期 |
2005.10.10 |
申请人 |
ONO PHARMACEUTICAL CO., LTD. |
发明人 |
ISHIDA, AKIHARU;NAKAYAMA, YOSHISUKE;KIDO, TOMOYUKI;KUSUDA, SHINYA;TAJIMA, HISAO;KITAMINE, TETSUYA |
分类号 |
A61K;A61P;A61P3/04;A61P3/06;C07C;C07C251/54;C07D;C07D207/20;C07D209/08;C07D211/70;C07D213/30;C07D213/50;C07D213/53;C07D213/55;C07D231/12;C07D233/54;C07D249/08;C07D257/04;C07D277/04;C07D295/13;C07D307/52;C07D319/08;C07D333/22;C07D403/12;C07D407/10;C07D407/12;C07D409/04;C07D417/10 |
主分类号 |
A61K |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|