The present invention provides an antibody which specifically recognizes three-dimensional structure of an extracellular region of a polypeptide encoded by PERP (p53 apoptosis effector related to PMP-22) gene and binds to the extracellular region. The antibody of the present invention is useful for treatment of various diseases which highly expresses a polypeptide encoded by the PERP gene. Also, a polypeptide encoded by the PERP gene or a cell expressing the polypeptide can be specifically detected by an immunological method using the antibody, so that the antibody is useful for diagnosis of various diseases related to PERP.
申请公布号
EP1767627(A1)
申请公布日期
2007.03.28
申请号
EP20050749067
申请日期
2005.06.07
申请人
KYOWA HAKKO KOGYO CO., LTD.;JAPAN AS REPRESENTED BY PRESIDENT OF NATIONAL CANCER CENTER
