发明名称 |
Monoclonal antibodies specific for buprenorphine and metabolites thereof |
摘要 |
The present invention relates to monoclonal antibodies that specifically bind buprenorphine and/or at least one metabolic product thereof. The present invention further relates to buprenorphine metabolite conjugates for the production of monoclonal antibodies that specifically bind buprenorphine and/or at least one metabolic product thereof and hybridoma cells that produce the monoclonal antibodies. The invention also relates to immunoassay methods for determining buprenorphine and/or one or more buprenorphine metabolites in a sample using the novel antibodies and conjugates of the present invention.
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申请公布号 |
US7195882(B2) |
申请公布日期 |
2007.03.27 |
申请号 |
US20030453256 |
申请日期 |
2003.06.03 |
申请人 |
ROCHE DIAGNOSTICS OPERATIONS, INC. |
发明人 |
ROOT RICHARD T.;GHOSHAL MITALI |
分类号 |
C07D451/00;C07D498/12;C07K16/44;C07K17/06;G01N33/94 |
主分类号 |
C07D451/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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