发明名称 Imidazoolverbindingen voor de behandeling van neurologische stoornissen.
摘要 The present invention relates to compounds of Formula I wherein R1, R2, R3, R4, R6, R7 and A are as defined. Compounds of Formula I have activity inhibiting production of A&bgr;-peptide. The invention also relates to pharmaceutical compositions and methods for treating diseases and disorders, for example, neurodegenerative and/or neurological disorders, e.g., Alzheimer's disease, in a mammal comprising compounds of Formula I.
申请公布号 NL1032552(A1) 申请公布日期 2007.03.23
申请号 NL20061032552 申请日期 2006.09.21
申请人 PFIZER PRODUCTS INC. 发明人 MICHAEL AARON BRODNEY;YUHPYNG LIANG CHEN;KAREN JEAN COFFMAN;EDWARD FOX KLEINMAN;BRIAN THOMAS O'NEILL
分类号 C07D233/88;A61K31/4168;A61K31/422;A61K31/4245;A61K31/4439;A61K31/454;A61K31/46;A61K31/496;A61K31/519;A61K31/5377;A61K31/5513;A61P25/00;C07D401/02;C07D403/02;C07D405/02;C07D409/02;C07D413/02;C07D417/02;C07D451/02;C07D487/08;C07D491/048 主分类号 C07D233/88
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