Process for the preparation of 1,2,3,4,8,9,10, 10a-octahydro-7bH-cyclopenta[b][1,4]diazepino-[6,7,1-hi]indole derivatives

摘要

This invention provides processes for preparing compounds formula: wherein R is H, alkyl, acyl, aryl, aroyl or -C(O)R'; R' is alkyl or aryl; R₁, R₂, R₄ and R₅ are H, -OH, alkyl, cycloalkyl, alkoxy, halogen, fluorinated alkyl or alkoxy, -CN, -NH-SO₂-alkyl, -SO₂-NH-alkyl, alkyl amide, amino, alkylamino, dialkylamino, acyl, aryl or aroyl; R₃ is H, alkyl, cycloalkyl, alkoxy, fluorinated alkyl, -NH-SO₂-alkyl, -SO₂-NH-alkyl, alkyl amide, amino, alkylamino, dialkylamino, fluorinated alkoxy, acyl, aryl, or aroyl; or a pharmaceutically acceptable salt thereof, as well as novel compounds useful in the synthesis of these compounds.