发明名称 |
HETEROCYCLIC COMPOUND, AND PRODUCTION PROCESS AND USE THEREOF |
摘要 |
<p>Disclosed is a novel compound which has a pyrazolonaphthyridine or pyrazoloquinoline skeleton, which shows an inhibitory effect on phosphodiesterase IV. In the compound, an organic group (e.g., a homocarbocyclic ring is bound to bound particularly to position 3 of a specific heterocyclic skeleton through an alkylene group, and a homocarbocyclic ring is bound particularly to position 5 of the heterocyclic skeleton. In the compound, at least one of the ring (the homocarbocyclic ring or heterocyclic ring) bound to position 3 of the pyrazolonaphthyridine skeleton and the homocarbocyclic ring bound to position 5 of the pyrazolonaphthyridine may have an alkyl halide group and/or an alkoxy halide group as a substituent. The compound or a salt thereof is useful as a phosphodiesterase IV inhibitor and shows a high inhibitory effect on phosphodiesterase IV.</p> |
申请公布号 |
WO2007032466(A1) |
申请公布日期 |
2007.03.22 |
申请号 |
WO2006JP318348 |
申请日期 |
2006.09.15 |
申请人 |
ASKA PHARMACEUTICAL CO., LTD.;KANAZAWA, HASHIME;AOTSUKA, TOMOJI;KUMAZAWA, KENTAROU;ISHITANI, KOUKI;NOSE, TAKASHI |
发明人 |
KANAZAWA, HASHIME;AOTSUKA, TOMOJI;KUMAZAWA, KENTAROU;ISHITANI, KOUKI;NOSE, TAKASHI |
分类号 |
C07D471/04;A61K31/4375;A61K31/4745;A61P1/02;A61P1/04;A61P1/16;A61P1/18;A61P3/04;A61P3/10;A61P5/00;A61P5/14;A61P5/38;A61P7/00;A61P7/02;A61P7/04;A61P7/06;A61P9/00;A61P9/04;A61P9/06;A61P9/10;A61P9/12;A61P11/00;A61P11/06;A61P13/08;A61P13/10;A61P13/12;A61P15/00;A61P15/08;A61P15/10;A61P17/00;A61P17/02;A61P17/04;A61P17/06;A61P17/14;A61P19/02;A61P21/00;A61P21/02;A61P21/04;A61P25/00;A61P25/02;A61P25/08;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P27/02;A61P27/16;A61P29/00;A61P31/04;A61P31/12;A61P31/18;A61P35/00;A61P35/02;A61P37/02;A61P37/04;A61P37/06;A61P37/08;A61P43/00;C07D471/14 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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