Human PF4A receptors, nucleic acid encoding and antibodies binding thereto

摘要

cDNAs encoding a class of receptors, including the IL-8 receptor, have been identified in human tissue. Recombinantly produced PF4ARs are used in the preparation and purification of antibodies capable of binding to the receptors, and in diagnostic assays. The antibodies are advantageously used in the prevention and treatment of inflammatory conditions.