| 发明名称 |
INHIBITORS OF HUMAN PLASMIN DERIVED FROM THE KUNITZ DOMAINS |
| 摘要 |
This invention relates to novel mutants of the first Kunitz domain (K1) of t he human lipoprotein-associated coagulation inhibitor (LACI) which inhibit plasmin. The invention also relates to other modified Kunitz domains that inhibit plasmin and to other plasmin inhibitors.
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| 申请公布号 |
CA2180954(C) |
申请公布日期 |
2007.03.20 |
| 申请号 |
CA19952180954 |
申请日期 |
1995.01.11 |
| 申请人 |
PROTEIN ENGINEERING CORPORATION |
发明人 |
MARKLAND, WILLIAM;LADNER, ROBERT CHARLES |
| 分类号 |
C07K14/81;C12N15/09;A61K38/55;A61K38/57;A61K51/00;A61P7/04;C04B35/593;C12N9/68;C12Q1/37;C12Q1/56 |
主分类号 |
C07K14/81 |
| 代理机构 |
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