发明名称 |
Nukleotidsekvens, der koder for en flavinmonooxygenase, det tilsvarende protein og deres anvendelser inden for diagnostik og terapi |
摘要 |
The present invention concerns, in particular, human flavin-containing monooxygenase 2 (hFMO2), and another human enzyme of the FMO, hFMOx family, their nucleotide and polypeptide sequences. The present invention also concerns vectors for cloning and/or expression containing said nucleotide sequences and cells transformed by these vectors and method for preparing said polypeptides. The invention further concerns methods for selecting compounds and of diagnosing predisposition to pathologies and/or deficiencies related to FMO's and pharmaceutical compositions containing said compounds for treating and/or preventing these pathologies. |
申请公布号 |
DK0941341(T3) |
申请公布日期 |
2007.03.19 |
申请号 |
DK19970950244T |
申请日期 |
1997.12.05 |
申请人 |
SERONO GENETICS INSTITUTE S.A.;INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) |
发明人 |
GARCHON, HENRI-JEAN;BLUMENFELD, MARTA;BACH, JEAN-FRANCOIS;TCHOUMAKOV, ILIA |
分类号 |
C12N15/09;C12N15/86;A61K36/06;A61K38/00;A61K38/44;A61K39/395;A61K45/00;A61K48/00;A61P1/04;A61P9/08;A61P9/12;A61P25/00;A61P25/24;C07K16/40;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/02;C12N15/11;C12N15/53;C12P21/02;C12P21/08;C12Q1/26;C12Q1/68;G01N33/50;G01N33/573 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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