USE OF NUCLEASES TO IMPROVE VIABILITY AND ENHANCE TRANSGENE EXPRESSION IN TRANSFECTED CELLS
摘要
The present invention concerns methods and compositions for improving viability and transgene expression in transfected cells. In one embodiment, the present invention provides a method for increasing the viability of a transfected cell, the method comprising: transfecting a cell with a nucleic acid sequence; and contacting the transfected cell with a nuclease in a manner effective to enhance the viability of the transfected cell.
申请公布号
WO2007030674(A2)
申请公布日期
2007.03.15
申请号
WO2006US34955
申请日期
2006.09.07
申请人
MAXCYTE, INC.;LI, LINHONG;LIU, LINDA, N.;ALLEN, CORNELL;SHIVAKUMAR, RAMA;BRADY, JAMES
发明人
LI, LINHONG;LIU, LINDA, N.;ALLEN, CORNELL;SHIVAKUMAR, RAMA;BRADY, JAMES