| 发明名称 |
Anti-interferon-alpha antibodies |
| 摘要 |
The present invention relates generally to the generation and characterization of neutralizing anti-IFN-alpha monoclonal antibodies with broad reactivity against various IFN-alpha subtypes. The invention further relates to the use of such anti-IFN-alpha antibodies in the diagnosis and treatment of disorders associated with increased expression of IFN-alpha, in particular, autoimmune disorders such as insulin-dependent diabetes mellitus (IDDM) and systemic lupus erythematosus (SLE).
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| 申请公布号 |
US2007059309(A1) |
申请公布日期 |
2007.03.15 |
| 申请号 |
US20060373527 |
申请日期 |
2006.03.10 |
| 申请人 |
GENENTECH, INC. |
发明人 |
CHUNTHARAPAI ANAN;KIM JIN K.;PRESTA LEONARD G.;STEWART TIMOTHY |
| 分类号 |
A61K39/395;G01N33/53;A61P3/10;A61P5/14;A61P5/50;A61P17/00;A61P37/02;A61P37/06;C07H21/04;C07K16/24;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/06;C12N5/10;C12N5/16;C12N5/20;C12N15/02;C12N15/09;C12N15/13;C12P21/02;C12P21/06;C12P21/08;G01N33/564;G01N33/68 |
主分类号 |
A61K39/395 |
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