发明名称 |
PRODRUGS OF T3 AND T4 WITH ENHANCED BIOAVAILABILITY |
摘要 |
The invention relates to compositions of amino acid and peptide conjugates comprising T3 and/or T4. The T3 or T4 is covalently attached to at least one amino acid via the N-terminus, the C-terminus, a side chain of the peptide carrier, and/or interspersed within the peptide chain. Also discussed are methods for protecting and administering active agents and methods for treating thyroid disorders. |
申请公布号 |
CA2621847(A1) |
申请公布日期 |
2007.03.15 |
申请号 |
CA20062621847 |
申请日期 |
2006.09.08 |
申请人 |
SHIRE LLC |
发明人 |
PICCARIELLO, THOMAS;OLON, LAWRENCE;MONCRIEF, JAMES SCOTT;MICKLE, TRAVIS |
分类号 |
C12P13/04;A01N37/18 |
主分类号 |
C12P13/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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