| 发明名称 |
THIOPHENE AND THIAZOLE SUBSTITUTED TRIFLUOROETHANONE DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS |
| 摘要 |
The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt or stereoisomer thereof. The compounds of t he present invention are inhibitors of histone deacetylase (HDAC) and are usefu l for treating cellular proliferative diseases, including cancer. Further, the compounds of the present invention are useful for treating neurodegenerative diseases, schizophrenia and stroke among other diseases.
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| 申请公布号 |
CA2621443(A1) |
申请公布日期 |
2007.03.15 |
| 申请号 |
CA20062621443 |
申请日期 |
2006.09.05 |
| 申请人 |
ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA |
发明人 |
FERRIGNO, FEDERICA;JONES, PHILIP;MURAGLIA, ESTER;ONTORIA ONTORIA, JESUS MARIA;SCARPELLI, RITA |
| 分类号 |
C07D333/38;A61K31/381;A61K31/426;A61P25/18;A61P25/28;A61P35/00;C07D277/56;C07D333/34;C07D409/08;C07D409/12;C07D409/14;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D471/04;C07D471/18;C07D487/04;C07D487/08;C07D487/18;C07D491/10;C07D495/04;C12Q1/34 |
主分类号 |
C07D333/38 |
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