发明名称 THIOPHENE AND THIAZOLE SUBSTITUTED TRIFLUOROETHANONE DERIVATIVES AS HISTONE DEACETYLASE (HDAC) INHIBITORS
摘要 <p>The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt or stereoisomer thereof. The compounds of the present invention are inhibitors of histone deacetylase (HDAC) and are useful for treating cellular proliferative diseases, including cancer. Further, the compounds of the present invention are useful for treating neurodegenerative diseases, schizophrenia and stroke among other diseases.</p>
申请公布号 WO2007029035(A2) 申请公布日期 2007.03.15
申请号 WO2006GB50274 申请日期 2006.09.05
申请人 ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA;FERRIGNO, FEDERICA;JONES, PHILIP;MURAGLIA, ESTER;ONTORIA ONTORIA, JESUS MARIA;SCARPELLI, RITA 发明人 FERRIGNO, FEDERICA;JONES, PHILIP;MURAGLIA, ESTER;ONTORIA ONTORIA, JESUS MARIA;SCARPELLI, RITA
分类号 C07D333/38;C07D277/56;C07D333/34;C07D409/06;C07D409/08;C07D409/12;C07D409/14;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D471/04;C07D471/18;C07D487/04;C07D487/08;C07D487/18;C07D491/10;C07D495/04;C12Q1/34 主分类号 C07D333/38
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