METHODS FOR DETERMINING THE PATHOGENICITY OF VIRAL STRAINS

摘要

Methods and compositions are provided for rapidly detecting the presence and lytic potential of a pathogenic virus in a sample and for determining the pathogenicity of a viral strain to cells, as compared to merely detecting the presence of viruses in a sample. Assays determine the pathogenicity of viral strains based on the viral strains' ability to expose nuclease sites on the host cell's nuclear DNA (e.g., condensed chromatin in malignant cells) to a DNA nuclease.