PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE a-SUBSTITUTED MANDELIC ACID COMPOUND

摘要

Disclosed is a process for production of an optically active a-substituted mandelic acid compound (a compound useful as an intermediate for synthesis of a pharmaceutical or the like) in an industrially advantageous manner. The process comprising the steps of reacting a compound (I) with a compound (II) in the presence of an optically active cyclic secondary amine to yield a compound (III) and producing a compound (VI) via a compound (V): wherein each symbol is as defined in the description.