5-Oxo-5,8-dihydro-pyrido-pyrimidines as inhibitors of c-fms kinase

摘要

The invention addresses the current need for selective and potent protein tyrosine kinase inhibitors by providing potent inhibitors of c-fms kinase. The invention is directed to the novel compounds of Formula I: or a solvate, hydrate, tautomer or pharmaceutically acceptable salt thereof, wherein:W, A, Y, n, Z, and R¹⁰² are described in the specification.