发明名称 |
Chaperonin-target protein complex, method of producing the same, method of stabilizing target protein, method of immobilizing target protein, method of analyzing the structure of target protein, sustained-release formulation, and method of producing antibody against target protein |
摘要 |
The present invention provides a chaperonin-target protein complex and a method of producing the same, and a method of stabilizing the target protein, a method of immobilizing the target protein, a method of analyzing the structure of the target protein, a sustained-release formulation, and a method of producing an antibody against the target protein. The chaperonin-target protein complex in the present invention includes a fusion protein having a chaperonin subunit and an affinity tag linked to the chaperonin subunit via a peptide bond and a target protein for which the affinity tag shows a specific affinity, wherein the target protein is bound to the affinity tag by means of the specific affinity, thereby forming a chaperonin ring structure consisting of a plurality of chaperonin subunits. The chaperonin-target protein in the present invention stabilizes the target protein and surely immobilize on a carrier without causing any change in its stereostructure.
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申请公布号 |
US2007059794(A1) |
申请公布日期 |
2007.03.15 |
申请号 |
US20040554747 |
申请日期 |
2004.04.28 |
申请人 |
SEKISUI CHEMICAL COMPANY LIMITED |
发明人 |
IDENO AKIRA;HATA JUN-ICHI;TOGI AKIKO;FURUTANI MASAHIRO |
分类号 |
C12P21/06;A61K38/17;C07H21/04;C12N9/64;C12N15/62;C12P21/08;G01N33/68 |
主分类号 |
C12P21/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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