Antiarrhythmic Precursor Compounds, Methods Of Synthesis And Methods Of Use

摘要

The invention comprises compounds of Formula 1: wherein, R₁ is independently H or halogen; R₂ is, for example, H or -R₁₀-NR₁₁R₁₂, and wherein R₁₀ is C₁-C₆ alkyl, and R₁₁ and R₁₂ are independently H, C₁-C₄ alkyl, and hydrates, solvates, salts and tautomers thereof. The invention further comprises methods for making the compounds of the invention and methods for making compounds useful in the treatment or prevention of cardiac arrhythmia from the compounds of the invention.