发明名称 PEPTIDES FOR REGULATION OF UROKINASE (UPA) AND TISSUE TYPE (TPA) PLASMINOGEN ACTIVATOR AND METHOD OF OPTIMIZING THERAPEUTIC EFFICACY
摘要 The present invention relates to compositions of the polypeptide EEIIMI, anti-LRP antibodies, LRP antagonists, and/or one or more fibrinolytic agents comprising scuPA, tPA, uPA, tcuPA, streptokinase, rt-PA, alteplase, rt-PA derivatives, reteplase, lanoteplase, TNK-rt-PA, anisoylated plasminogen streptokinase complex, anistreplase, or a streptokinase derivative. The invention further relates to methods of enhancing the fibrinolytic activity, reducing the side effects due to vasoactivity caused by the fibrinolytic agents, and/or prolonging the half lives of the fibrinolytic agents.
申请公布号 EP1507547(A4) 申请公布日期 2007.03.14
申请号 EP20030711550 申请日期 2003.03.12
申请人 THROMBOTECH LTD 发明人 HIGAZI, ABD-AL-ROOF
分类号 A61K38/00;A61K38/02;A61K38/16;A61K38/49;A61K39/395 主分类号 A61K38/00
代理机构 代理人
主权项
地址