发明名称 |
TREATMENT WITH AN ONCOLYTIC VIRUS AND AN IMMUNOSTIMULANT FOR IN VIVO ENHANCEMENT OF IMMUNE SYSTEM RECOGNITION OF NEOPLASMS |
摘要 |
<p>This invention provides novel methods of treating or alleviating neoplasms in a mammal and enhancing the efficacy of oncolytic viruses by using a combination of an oncolytic virus and an immunostimulant, comprising administering a reovirus to a host and enhancing an immune response by the addition of an immunostimulant such as a CpG oligodeoxynucleotide or at least one antigen of said virus that is delivered to a host by dendritic cells.</p> |
申请公布号 |
CA2621127(A1) |
申请公布日期 |
2007.03.08 |
申请号 |
CA20062621127 |
申请日期 |
2006.08.22 |
申请人 |
ONCOLYTICS BIOTECH INC. |
发明人 |
COFFEY, MATTHEW C.;THOMPSON, BRADLEY G. |
分类号 |
A61K39/39;A61K31/00;A61K31/7084;A61K35/76;A61P35/00;A61P37/04;C07H21/04;C12N7/00 |
主分类号 |
A61K39/39 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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