摘要 |
The present invention relates to a stable liquid formulation comprising desoximetasone, isopropyl myristate, a C<SUB>2</SUB>-C<SUB>4</SUB> alcohol and a stabilizing agent. Specifically, the present invention provides a liquid formulation comprising: a) about 0.01 wt % to about 2.5 wt % desoximetasone; b) about 10 wt % to about 70 wt % isopropyl myristate; c) about 20 wt % to about 70 wt % C<SUB>2</SUB>-C<SUB>4</SUB> alcohol; and d) a stabilizing agent selected from the group consisting of an oleaginous vehicle and a propellant, wherein the stabilizing agent is in an amount sufficient to reduce the formation of less than about 1 wt % 17-carboxy-9a-fluoro-11ß-hydroxy-16a-methyl-androsta-1,4-diene-3-one under an accelerated storage condition. |
申请人 |
RAO, SRINVISA;DIXIT, SURESH;YACOBI, AVRAHAM;BAILEY, ARTHUR |
发明人 |
RAO, SRINVISA;DIXIT, SURESH;YACOBI, AVRAHAM;BAILEY, ARTHUR |