Disclosed is a polypeptide comprising at least two microproteins, which preferably comprise an amino acid sequence having a specific binding activity to a target protein. Furthermore, disclosed are polynucleotides encoding such a polypeptide as well as pharmaceutical compositions and kits comprising said polypeptide or polynucleotide. Also disclosed herein are methods of treatments and second medical uses applying the disclosed polypeptide or polynucleotide. Additionally, the disclosure of the present application relates to a method for forming a covalent bond in a microprotein which can be used for producing the disclosed polypeptides.
申请公布号
WO2006094813(A3)
申请公布日期
2007.03.08
申请号
WO2006EP02188
申请日期
2006.03.09
申请人
NASCACELL IP GMBH;WENTZEL, ALEXANDER;KOLMAR, HARALD;BOEHNLEIN, ERNST;SCHMOLDT, HANS-ULRICH