发明名称 METHOD FOR IN VITRO PRECONDITIONING OF MYOBLASTS BEFORE TRANSPLANTATION
摘要 <p>Methods of pre-treating healthy donor's myoblast cultures with growth or trophic factors on transplantation into subjects suffering from myopathic conditions such as muscular dystrophy. Compositions comprising myoblasts and fusion-promoting metalloproteases can be transplanted. Alternatively, myoblasts can be transplanted along with an agent inducing the expression of a fusion-promoting metalloprotease, or a composition comprising genetically-modified myoblasts capable of expressing a fusion-promoting metalloprotease can be transplanted.</p>
申请公布号 EP0946713(B1) 申请公布日期 2007.03.07
申请号 EP19970944670 申请日期 1997.10.17
申请人 UNIVERSITE LAVAL 发明人 TREMBLAY, JACQUES, P.
分类号 A61K35/12;A61K38/00;A61K48/00;C12N5/077;C12N5/10 主分类号 A61K35/12
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