发明名称 |
MICROBIOLOGICAL METHOD FOR PRODUCING L-CARNITINE |
摘要 |
The invention relates to a method for producing L-carnitine on the basis of a betaine ester of the general formula (I), wherein R<1> and R<2> represent either hydrogen or together form a bond, and R<3> represents alkyl, aryl or arylalkyl, by means of hydrolases that convert said betaine ester to give the betaine. The betaine so obtained is then converted to L-carnitine by means of a microorganism capable of converting the betaine of formula (II) to L-carnitine. The invention further relates to hydrolases that convert 4-butyrobetaine methyl ester to 4-butyrobetaine and to microorganisms that contain such hydrolases. |
申请公布号 |
EP1370663(B1) |
申请公布日期 |
2007.03.07 |
申请号 |
EP20020712878 |
申请日期 |
2002.01.31 |
申请人 |
LONZA AG |
发明人 |
BORNSCHEUER, UWE;MUSIDLOWSKA, ANNA;WERLEN, JOSEF;ZIMMERMANN, THOMAS;TSCHERRY, BENNO |
分类号 |
C12N15/55;C12N1/21;C12N9/18;C12P13/00;C12R1/01;C12R1/41 |
主分类号 |
C12N15/55 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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