发明名称 Methods of modulating cell migration using galectin-3
摘要 The present invention relates to methods of modulating cell migration, particularly, monocyte, neutrophil or macrophage migration, using galectin-3, galectin-3 binding polypeptide, or galectin-3 receptor binding polypeptide. Specifically provided are methods for increasing cell migration to sites of inflammation, infection or a tumor. Also provided are methods for identifying agents that modulate galectin-3 mediated migration, compositions containing galectin-3 or a functional subsequence thereof, and microfabricated devices that deliver galectin-3 or functional galectin-3 subsequences.
申请公布号 US7186681(B2) 申请公布日期 2007.03.06
申请号 US20010805449 申请日期 2001.03.13
申请人 LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY 发明人 LIU FU-TONG;SANO HIDEKI;HSU DANIEL K.
分类号 A01N37/18;A61K38/00;A61K38/17;A61K39/395;A61K45/06;A61L26/00;A61L27/22;A61L27/54;C07K16/18;G01N33/50 主分类号 A01N37/18
代理机构 代理人
主权项
地址