发明名称 |
Nucleic acid delivery system, methods of synthesis and use thereof |
摘要 |
A nucleic acid delivery system is described. The delivery system contains a fusion protein having a target moiety and a nucleic acid binding moiety, and a nucleic acid sequence bound to the nucleic acid binding moiety of the fusion protein. The target moiety can be an antibody or a ligand. The use of this nucleic acid delivery system to transienntly or stably express a desired nucleic acid sequence in a cell is disclosed. Also disclosed is the use of this delivery system to target a cell and deliver a desired product.
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申请公布号 |
US7186697(B2) |
申请公布日期 |
2007.03.06 |
申请号 |
US19970822033 |
申请日期 |
1997.03.24 |
申请人 |
DANA-FARBER CANCER INSTITUTE |
发明人 |
MARASCO WAYNE A.;CHEN SI-YI |
分类号 |
A61K31/70;C12N15/09;A61K39/395;A61K47/48;A61K48/00;A61P35/00;C07H21/02;C07H21/04;C07K1/00;C07K14/46;C07K19/00;C12N15/62;C12N15/87 |
主分类号 |
A61K31/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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