This invention generally relates to Indoloquinone caused tumor radiation therapy sensitization. More specifically, this invention relates to the discovery of indoloquinones as a radiation sensitizer (radiation therapy adjuvant) due to its ability to selectively target hypoxic cells and to damage the DNA of these hypoxic cells. Indoloquinones do so with minimal normal cell and tissue toxicity.
申请公布号
WO2006105507(A3)
申请公布日期
2007.03.01
申请号
WO2006US12383
申请日期
2006.03.31
申请人
SPECTRUM PHARMACEUTICALS, INC.;BURD, RANDY;LENAZ, LUIGI;CHAWLA, SHANTA;REDDY, GURU;DICKER, ADAM, P.
发明人
BURD, RANDY;LENAZ, LUIGI;CHAWLA, SHANTA;REDDY, GURU;DICKER, ADAM, P.