<p>This invention relates to compounds which modulate receptors of the 5-HT2 family of receptors, and particularly to compounds which modulate 5-HT2C receptors. Compounds of the invention include agonists and selective agonists for the 5-HT2C receptor. Compounds of the invention include selective agonists for the 5-HT2C receptor which exhibit significantly less or no agonist activity on the 5-HT2A receptor and/or the 5-HT2B receptor. Compounds of this invention are those of Formula I and pharmaceutically acceptable salts, esters and solvates (including hydrates) wherein variables are defined in the specification hereof.</p>
申请公布号
WO2007025144(A1)
申请公布日期
2007.03.01
申请号
WO2006US33251
申请日期
2006.08.24
申请人
UNIVERSITY OF ILLINOIS - CHICAGO;KOZIKOWSKI, ALAN;KUROME, TORU;SETOLA, VINCENT;ROTH, BRYAN