CRYSTAL STRUCTURE OF HOMO SAPIENS ADIPOCYTE LIPID BINDING PROTEIN AND USES THEREOF

摘要

The invention is directed generally to the structure of lipid binding proteins, particularly human lipid binding protein (aP2), a protein important in adipocyte function. The invention also relates to the use of a crystal structure of human lipid binding protein or mutants and the interaction with ligands for the design of inhibitors. Furthermore, the invention relates to the structure of ligand binding sites.