| 摘要 |
Methods for evaluating surface-bound polynucleotides, e.g., candidate aCGH probe nucleic acids, are provided. Specifically, the methods involve contacting an array of surface-bound polynucleotides with a validation nucleic acid composition and assessing binding of the surface-bound polynucleotides. The methods may be used to screen for surface bound polynucleotides that have desirable binding characteristics, e.g., suitability for use in array-based comparative genomic hybridization assays.
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