Calcium phosphate ceramics and particles for in vivo and in vitro transfection

摘要

The invention relates to a method of modifying the surface of calcium phosphate ceramics and powders. The inventive method involves maturation in a culture medium, thereby causing epitaxial carbonated apatite growth at the surface of the aforementioned ceramics and powders. The invention also relates to the use of said modified ceramics and powders for in vitro and in vivo cell transfection and for cell culture in a three-dimensional network.