REGULATION OF HETEROLOGOUS RECOMBINANT PROTEIN EXPRESSION IN METHYLOTROPHIC AND METHANOTROPHIC BACTERIA
摘要
<p>Methylotrophic or methanotrophic bacteria such as Methylobacterium are transformed with a gene of interest, and expression of the gene is regulated by means of a cumate repressor protein and an operator sequence which is operatively linked to the gene of interest, and the addition of an external agent. Specifically, the cymR repressor and cmt operator from Pseudomonas putida may serve to regulate gene expression in methylotrophic or methanotrophic bacteria with the addition of cumate.</p>
申请公布号
WO2007022623(A1)
申请公布日期
2007.03.01
申请号
WO2006CA01371
申请日期
2006.08.21
申请人
NATIONAL RESEARCH COUNCIL OF CANADA;MIGUEZ, CARLOS B.;CHOI, YOUNG-JUN;MULLICK, ALAKA;MASSIE, BERNARD
发明人
MIGUEZ, CARLOS B.;CHOI, YOUNG-JUN;MULLICK, ALAKA;MASSIE, BERNARD